禽源呼肠孤病毒诱导宿主免疫应答研究进展

doi:10.11843/j.issn.0366-6964.2017.12.004

Abstract

Abstract:

Avian-origin reovirus, which is a kind of important poultry and waterfowl pathogen, can cause serious damage to the bursa of Fabricius, spleen and thymus of infected birds, resulting in immunosuppression and increased susceptibility to secondary diseases that greatly hinder the healthy development of global poultry and waterfowl industry. The innate immune response is the hotspot in the field of microbiology and immunology due to its earlier and quick non-specific response against pathogens. Adaptive immune response can eliminate the intruding pathogens,and defend against reinfection of the same pathogens, which provides immunological basis for the immunization of host. In this review, we highlight the current understanding of host innate immune response and adaptive immune response induced by avian-origin reovirus and the effects of such virus infection on the host immune system. This review will provide a basis for understanding the virus-host interaction and vaccine development.

CLC Number:

CHI Xiao-juan, SHAO Wen-han, CHEN Ji-long, CHEN Yue-xiang, WANG Song. The Research Advance of Host Immune Response Induced by Avian-origin Reovirus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(12): 2249-2257.

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The Research Advance of Host Immune Response Induced by Avian-origin Reovirus

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